Cytogenetics is the field of genetics, which studies the cytological mechanisms of heredity, the functional organization of chromosomes. The use of molecular cytogenetic methods (fluorescence in situ hybridization (FISH), next –generation sequencing (NGS), microarray based comparative genomic hybridization (array CGH) allowed to increase the resolving power of cytogenetic analysis. The most important properties of heredity are conservatism (stability) and variability (instability), which can be adaptive in nature, and lead to pathology. Genomic instability is found in clinical syndromes, in tumor cells, as well as in the genome of patients with mental illnesses, congenital malformations and individuals exposed to chemical mutagens and radiation.
The following fundamental questions will be discussed at the conference:
The discussion of the fundamental causes of genomic instability will allow initiating Russian and International joint research. The section for young scientists is planned to be held at the conference, where they will make presentations. One section will be devoted to modern methods of cytogenetics. A quiz, a master class about interpretation of genotype-phenotype data, a competition "Find a chromosomal abnormality", an exhibition of cytogenetic photography will be organized.
The event will be take place at Saint Petersburg.